Pfizer says 1 patient death in oral rheumatoid arthritis study was related to its drug

NEW YORK (AP) -- Pfizer Inc. confirmed that one patient who was taking its drug candidate tofacitinib, a pill designed to treat rheumatoid arthritis, died during a recent clinical trial and said the death was connected to the drug.

The world's largest drugmaker said the patient died of respiratory failure. Three other patients who were treated with tofacitinib during the study died as well, but those deaths were not determined to be drug-related. Two of those deaths occurred several weeks after the patients stopped taking tofacitinib. Tofacitinib, formerly called tasocitinib, is being tested as a treatment for moderate to severe rheumatoid arthritis, a chronic autoimmune disease that causes inflammation, usually of the hands and feet.

'Birther' claims force GOP leaders to take a stand

WASHINGTON (AP) -- It's the conspiracy theory that won't go away. And it's forcing Republican officials and presidential contenders to pick sides: Do they think Barack Obama was born outside the United States and disqualified to be president?

As the Republican candidates tiptoe through the minefield, Democrats are watching. They hope the debate will fire up their liberal base and perhaps tie the eventual GOP nominee to fringe beliefs that swing voters will reject.